ICR Steering Committee Through July 31, 2009    

The ICR was an interactive group of laboratories whose primary purpose was to supply investigators with clinical grade islets for ICR-approved studies. The Steering Committee (SC) oversaw the general functions of the ICR, based on the Policy and Procedures document, and evaluated the clinical and scientific merit of submitted applications. The SC determined through the adoption of the Matching Algorithm for Islet Distribution (MAID) which ICR facility would produce the islets for each ICR-approved request. The ICR SC was informed of, and monitored serious adverse events involving ICR-supported protocols when the clinical investigator reported them to local and Federal oversight groups in accordance with institutional, state, and Federal guidelines. The SC did not serve as a Data and Safety Monitoring Board for individual transplantation protocols.

The ICR Steering Committee was comprised of the chairman, the Administrative and Bioinformatics Coordinating Center (ABCC) Director, 10 ICR directors, 2 outside experts, a Food and Drug Administration (FDA) representative, a National Institutes of Diabetes and Digestive Kidney Diseases (NIDDK) representative, a Juvenile Diabetes Research Foundation International (JDRFI) representative, and a National Center for Research Resources (NCRR) representative.