The Marquette Hotel, Minneapolis, MN
Thursday, August 24, 2006

I. Beta Cells and Islets:
a. Recent Progress in Beta Cell Biology   Session Chair: Gordon Weir, Joslin Diabetes Center
  1. Per-Olof Berggren, Karolinska Institute
“Signal-Transduction in Pancreatic B-Cell Function and Survival”
PowerPoint Presentation Abstract
  2. John A. Corbett, St. Louis University
“How Do Cytokines Kill Beta Cells?”
PowerPoint Presentation Abstract
b. Predictive Islet Potency Testing   Session Chair: Bernhard Hering, University of Minnesota
  1. Robert Kennedy, University of Michigan
“Microfluidics, Sensors and Metabolomics: Can These Tools Aid Evaluation of Transplantable Islets?”
PowerPoint Presentation Abstract
  2. Olle Korsgren, Uppsala University
Title: Pending
PowerPoint Presentation Abstract
  3. Philip J. O’Connell, Westmead Hospital
“Novel Approaches to Identifying Islets Criteria that Predict Clinical Outcomes”
PowerPoint Presentation Abstract
  4. Christopher Rhodes, University of Chicago
“A ß-Cell Functional Differentiation Diagnostic Laboratory - for Human Islets and Candidate ß-Cells Alike”
PowerPoint Presentation Abstract
Optional Lunch Tour Being Offered (Must sign up – limited space available):
University of Minnesota ICR Islet Isolation Facility
II. Collagenase Enzyme: Current Issues and Future Directions:
a. Session I   Chair (Sessions I-III): Jonathan R.T. Lakey,
University of Alberta, Edmonton
  1. Federico Bertuzzi, ISMETT
“Characterization of Successful Collagenase Blend Enzymes for Human Islet Isolation”
PowerPoint Presentation Abstract
  2. Daniel Brandhorst, Uppsala University
“The Importance of Collagenase Class I and II for Islet Isolation Outcome: A Prospective Study”
PowerPoint Presentation Abstract
  3. A.N. Balamurugan, University of Colorado
“Secondary Negative Effects of Isolation Enzyme(s) on Human Islets”
PowerPoint Presentation Abstract
b. Session II    
  1. Vladimir Malinovskii, University of Miami DRI
“Characterization, Assessment, and Autoproteolysis in Commercial Blends of
Clostidial Collagenases Used for Human Islets Isolation”
PowerPoint Presentation Abstract
c. Session III         
  1. Bob McCarthy, VitaCyte
“Purified Tissue Dissociation Enzymes: Past, Present, Future Challenges”
PowerPoint Presentation Abstract
Optional Hosted Dinner 7:30 pm – 10:00 pm in the Marquette Hotel’s Stars Salon