| AGENDA |
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| 7:30 am - 8:00 am |
Continental Breakfast |
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| 8:00 am - 8:20 am |
I. Overview |
Clark Colton, MIT |
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| 8:20 am - 11:30 am |
II. Mitochondrial Function Assays |
Chair: Ronald Gill, U. Colorado |
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A. Intact Islet Preps |
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1. Oxygen Consumption Rate |
Clark Colton, MIT Klearchos Papas, U.Minnesota Ian Sweet, U. Washington JoAnna Reems, Puget Sound Chris Fraker, U. Miami |
PowerPoint Presentation Abstract PowerPoint Presentation Abstract PowerPoint Presentation Abstract PowerPoint Presentation Abstract PowerPoint Presentation Abstract |
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| 11:30 am - 11:45 am |
Break |
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2. ATP/ADP Ratio |
Olle Korsgren, Uppsala U. |
PowerPoint Presentation Abstract |
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B. Individual Cells |
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1. Mito. Memb. Potential Measurements on B-cells |
Hirohito Ichii, U. Miami |
PowerPoint Presentation Abstract |
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| 1:00 pm - 2:00 pm |
Lunch Served |
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| 2:00 pm - 4:00 pm |
III. Assessments of Beta Cells |
Chair: Gordon Weir, Joslin |
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A. Apoptosis versus Replication |
Peter Butler, UCLA |
PowerPoint Presentation Abstract |
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B. Insulin Stimulation Index |
Olle Korsgren, Uppsala U. |
PowerPoint Presentation Abstract |
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1. Comments |
Alvin Powers, Vanderbilt U. Robert Chow, USC |
PowerPoint Presentation Abstract PowerPoint Presentation Abstract |
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C. Beta Cell Count |
Susan Bonner-Weir, Joslin |
PowerPoint Presentation Abstract |
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| 4:00 pm - 4:15 pm |
Break |
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| 4:15 pm - 6:15 pm |
IV. Animal Transplantation Studies |
Chair: Ronald Gill, U. Colorado |
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A. Use of Animal Models |
Ronald Gill, U. Colorado |
PowerPoint Presentation Abstract |
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B. Animal Model Correlations |
Klearchos Papas, U. Minnesota |
PowerPoint Presentation Abstract |
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C. Graft Function |
Leif Jansson, Uppsala U. |
PowerPoint Presentation Abstract |
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D. Bioluminescent Imaging |
Alvin Powers, Vanderbilt U. |
PowerPoint Presentation Abstract |
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| 7:00 pm - 7:45 pm |
Dinner* |
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| 7:45 pm - 9:15 pm |
V. Recombinant Collagenase |
Chair: Jonathan Lakey, U. Alberta |
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A. Types of Collagenase (general overview) |
Jonathan Lakey, U. Alberta |
PowerPoint Presentation Abstract |
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B. cCMP Collagenase |
Manfred Kurfuerst, Serva |
PowerPoint Presentation Abstract |
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C. Rationale for Good Digestion |
Paul R.V. Johnson, U. Oxford |
PowerPoint Presentation Abstract |
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